Happy Halloween! So this is the scariest picture we've got
Okay so it wasn’t that scary… It’s just a solitary keratoacanthoma (KA). A keratoacanthoma represents a proliferation of the squamous layer of the skin. Some doctors believe this to represent a spectrum of squamous carcinoma of the skin. Sun exposure is a risk factor. All patients with the lesion should get a dermatology referral and to rule out underlying squamous carcinoma. This lesion is often surgically removed to both look for skin cancer and improve the cosmetic appearance.
Neurofibromatosis Type-1 (NF-1) can have a number of clinical exam findings. A hallmark of NF-1 are the tumors that can be anywhere (most commonly cutaneous). However, if deeper, they can lead to lymphatic obstruction as seen in our patient.
The Stanford Medicine 25 website recently passed 500,000 total visits and 375,000 unique visits since our initial launch in February, 2012. We just wanted to thank everyone for all the support!…
DRESS is an immune response seen most commonly with certain drugs including anticonvulsants (lamotrigine, carbamazepine and phenytoin) and allopurinol. The diagnosis is usually made with a rash (such as in the picture) combined with eosinophilia and end-organ dysfunction (renal failure, transaminitis or lung involvement). Many other organs can be less commonly affected.