Hematology & Oncology

Stanford Medicine 25 Blog

  • What is the Sister Mary Joseph nodule?

    A 78 year woman presents with weight loss, lethargy and abdominal pain. Clinical examination showed abdominal distention and a firm, non-tender, irregular 1 cm nodule within the umbilicus...

  • What is Plummer-Vinson syndrome?

    A middle aged woman presents with difficulty swallowing. She has a history of menometrorrhagia for 10 years, secondary to uterine fibroids. She endorses fatigue and shortness of breath. What’s the cause of her dysphagia and why? Answer: Esophageal webs in the setting of iron deficiency anemia. This is seen in Plummer-Vinson syndrome. This syndrome usually has: dysphagia...

  • What is the Howell-Jolly body?

    This is a picture of a red blood cell with a Howell-Jolly body (red arrows). They are left over nuclear remnants that are usually removed when blood cells are in the spleen. Howell-Jolly bodies occur where there is no spleen or an non-functioning spleen, referred to as asplenia. They are usually one of these at most in a red cell, round, dark purple to red in color and often located peripherally on the red blood cell...

  • Dr. Rosenberg Teaches the Lymph Node & Spleen Exam

    Dr. Saul Rosenberg was first recruited to Stanford in 1961 and was involved in the creation of our hospital’s first lymphoma program. Today, Dr. Rosenberg shared his years of experience to lead our Stanford Medicine 25 session on the lymph node and spleen exam.

  • Lymph Node and Spleen Exam with Dr. Beth Martin

    Dr. Beth Martin led this week’s Stanford 25 session by teaching our residents how she exams for enlarged lymph nodes and an enlarged spleen.

  • Gingival Hyperplasia in Acute Leukemia

    Extramedullary involvement of leukemia can occur in up to 40% of patients. One of the rarest sites of extramedullary involvement is the oral cavity, with only 5% or less of all patients with AML present with gum infiltration.

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